High-Risk Neuroblastoma Relapse
Although outcomes have improved, children with high-risk neuroblastoma continue to face high mortality1,2
![](https://hcp.iwilfin.com/wp-content/uploads/2024/02/Rev_highrisk.png)
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The addition of maintenance therapy could offer your patients an additional layer of protection against relapse. When determining if maintenance therapy is right for your patient, consider these key objectives:
- Aligns with desired treatment goals for the patient
- Possesses an established and well tolerated safety profile
- Allows for normal or neal-normal resumption of a patient’s life
![](https://hcp.iwilfin.com/wp-content/uploads/2024/02/moa.png)
Learn more about IWILFIN’s unique mechanism of action.
![](https://hcp.iwilfin.com/wp-content/uploads/2024/02/safeandeffective.png)
Learn more about IWILFIN’s safety and efficacy.
References:
- 1. Sholler GLS, Ferguson W, Bergendahl G, et al. Maintenance DFMO increases survival in high risk neuroblastoma. Sci Rep. 2018;8(1):14445. doi:10.1038/s41598-018-32659-w
- 2. Shohet JM, Lowas SR, Nuchtern JG. Treatment and prognosis of neuroblastoma. Wolters Kluwer. UpToDate.com. Accessed December 15, 2023. Available at: https://www.uptodate.com/contents/treatment-and-prognosis-of-neuroblastoma
- 3. Batth IS, Dao L, Satelli A, et al. Cell surface vimentin positive circulating tumor cell-based relapse prediction in a long-term longitudinal study of post-remission neuroblastoma patients. Int J Cancer. 2020;147(12):3550-3559. doi:10.1002/ijc.33140
- 4. London WB, Bagatell R, Weigel BJ, et al. Historical time to disease progression and progression-free survival in patients with recurrent/refractory neuroblastoma treated in the modern era on Children’s Oncology Group early-phase trials. Cancer. 2017;123:4914-4923
- 5. Medicine.net. Life Expectancy of Neuroblastoma: Survival Rate & Prognosis. Accessed December 15, 2023. Available at: https://www.medicinenet.com/life_expectancy_of_a_child_with_neuroblastoma/article.html